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FITC標(biāo)記的含錨蛋白重復(fù)序列-細(xì)胞因子信號(hào)抑制物盒蛋白家族13抗體

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FITC標(biāo)記的含錨蛋白重復(fù)序列-細(xì)胞因子信號(hào)抑制物盒蛋白家族13抗體產(chǎn)品介紹：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

詳細(xì)介紹

英文名稱	Anti-ASB13/FITC
中文名稱	FITC標(biāo)記的含錨蛋白重復(fù)序列-細(xì)胞因子信號(hào)抑制物盒蛋白家族13抗體
別名	Ankyrin repeat and SOCS box containing 13; Ankyrin repeat and SOCS box containing protein 13; Ankyrin repeat and SOCS box protein 13; Ankyrin repeat domain containing SOCS box protein Asb 13; Ankyrin repeat domain containing SOCS box protein Asb13; ASB 13; ASB13_HUMAN.
說明書	100ul
研究領(lǐng)域	細(xì)胞生物免疫學(xué)
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit,
產(chǎn)品應(yīng)用	IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	30kDa
性狀	Lyophilized or Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human ASB13
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹	background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-13 (ankyrin repeat and SOCS box-containing 13) is a 278 amino acid member of the ASB family that contains one SOCS box domain and six ANK repeats. Existing as multiple isoforms, ASB-13 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Similarity: Contains 6 ANK repeats. Contains 1 SOCS box domain. Database links: UniProtKB/Swiss-Prot: Q8K3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.