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FITC標(biāo)記的AlkB同源蛋白8抗體

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商鋪產(chǎn)品：9811條

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產(chǎn)品簡介

FITC標(biāo)記的AlkB同源蛋白8抗體產(chǎn)品介紹：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

詳細介紹

英文名稱	Anti-ABH8/FITC
中文名稱	FITC標(biāo)記的AlkB同源蛋白8抗體
別名	ABH8; alkB alkylation repair homolog 8 (E. coli); alkB alkylation repair homolog 8; AlkB homologue 8; ALKB8_HUMAN; ALKBH8; Alkylated DNA repair protein alkB homolog 8; Probable alpha-ketoglutarate-dependent dioxygenase ABH8; S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8.
說明書	100ul
研究領(lǐng)域	腫瘤腫瘤細胞生物標(biāo)志物表觀遺傳學(xué)
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit,
產(chǎn)品應(yīng)用	IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	75kDa
性狀	Lyophilized or Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human ABH8/ALKBH8 (256-300aa)
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹	background: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis. Function: Catalyzes the methylation of 5-carboxymethyl uridine to5-methylcarboxymethyl uridine at the wobble position of theanticodon loop in tRNA. Catalyzes the last step in the formation of5-methylcarboxymethyl uridine at the wobble position of theanticodon loop in target tRNA. Has a preference for tRNA(Arg) andtRNA(Glu), and does not bind tRNA(Lys). Required for normalsurvival after DNA damage. May inhibit apoptosis and promote cellsurvival and angiogenesis. Subunit: Interacts with TRMT112. Subcellular Location: Cytoplasm. Nucleus. Note=Predominantlycytoplasmic. Tissue Specificity: Widely expressed, with highest expression inspleen, followed by pancreas and lung. Similarity: Belongs to the alkB family. Contains 1 Fe2OG dioxygenase domain. Contains 1 RRM (RNA recognition motif) domain.